Clinicopathological Characteristics of Early-Onset Colorectal Cancer(EOCRC)Cases in Our Hospital

In recent years, the number of colorectal cancer in Europe and the U. S. has been decreasing, but there are increasing reports on the trend of early-onset colorectal cancer(EOCRC), which is a rare population with no established knowledge on its characteristics. Of 3,501 colorectal cancer cases treat...

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Published inGan to kagaku ryoho Vol. 50; no. 13; p. 1367
Main Authors Yanagisawa, Kiminori, Ikeshima, Ryo, Hiraki, Masayuki, Hata, Taishi, Katsuyama, Shinsuke, Shinke, Go, Kinoshita, Mitsuru, Nomura, Hajime, Yanagawa, Takehiro, Ohshima, Kazuki, Ohmura, Yoshiaki, Sugimura, Keijiro, Masuzawa, Toru, Takeda, Yutaka, Murata, Kohei
Format Journal Article
LanguageJapanese
Published Japan 01.12.2023
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Summary:In recent years, the number of colorectal cancer in Europe and the U. S. has been decreasing, but there are increasing reports on the trend of early-onset colorectal cancer(EOCRC), which is a rare population with no established knowledge on its characteristics. Of 3,501 colorectal cancer cases treated at our hospital between April 2011 and December 2021, those aged 39 years and younger were included. There were 32 EOCRC cases, 11 males/21 females. The histological type was tub in 31 cases and por in 1 case. Postoperative adjuvant chemotherapy was administered in 14 patients, and 12 completed the scheduled course. Twenty nine patients underwent R0 resection, of which 6 patients had recurrence and 5 patients died of primary disease. In summary, although EOCRC patients were in good general condition and had a high completion rate of adjuvant chemotherapy, the relapse rate was high, suggesting the need for aggressive adjuvant chemotherapy and careful postoperative surveillance.
ISSN:0385-0684