Operative efficacy of 13 malignant uterine tumors after Cf-252 intracavitary irradiation

• Published in: Zhōnghuá zhŏngliú zázhì Vol. 42; no. 10; pp. 882 - 884
• Main Authors: Bai, P, Bu, J, Li, R, Sun, P, Sun, H, Sun, J H
• Format: Journal Article
• Language: Chinese
• Published: China 23.10.2020
• Subjects: Brachytherapy; Californium - therapeutic use; Female; Humans; Hysterectomy; Uterine Neoplasms - radiotherapy; Uterine Neoplasms - surgery; Endometrial neoplasms; Surgery; Cf-252 brachytherapy; Uterine neoplasms
• ISSN: 0253-3766
• DOI: 10.3760/cma.j.cn112152-20190903-00570

To investigate the surgical therapeutic efficacy of uterine tumors patients underwent Cf-252 neutron intra-cavity and external radiotherapy, and evaluate the application value of Cf-252 neutron radiotherapy. Thirteen cases of uterine tumor with local suspicious lesions or poor prognostic factors after CF-252 neutron intracavity and external radiotherapy were treated with surgery. Among them, 12 cases underwent extrafascial hysterectomy, 1 case underwent extensive hysterectomy and lymphadenectomy. The postoperative pathology and follow-up results were used to evaluate the efficacy. Nine cases showed severe response to radiotherapy in postoperative cervical pathological tissues without residual tumor, and survived for more than 3-14 years, the median survival time was 8 years. All of 4 cases with residual tumor died within 1 year. Delayed healing of vaginal wounds occurred in 3 of the 12 cases. Cf-252 is a good brachytherapy source. The cervical tissue shows severe response to radiotherapy and prolonged healing