Kikuchi's disease: an uncommon cause of cervical lymphadenopathy

Kikuchi Fujimoto's disease is a benign self limiting disorder presenting with localised cervical lymphadenopathy, fever, weight loss and night sweats. It is a rare disease with worldwide distribution but commonly reported from Asia. It is diagnosed by excision biopsy of the lymph nodes. Clinica...

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Bibliographic Details
Published inJournal of the Indian Medical Association Vol. 112; no. 1; p. 51
Main Authors Murali, A, Narasimhalu, C R V, Madhavan, M, Sujithkumar, S
Format Journal Article
LanguageEnglish
Published India 01.01.2014
Subjects
Female
Histiocytic Necrotizing Lymphadenitis - diagnosis
Histiocytic Necrotizing Lymphadenitis - therapy
Humans
Neck
Young Adult
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Summary:Kikuchi Fujimoto's disease is a benign self limiting disorder presenting with localised cervical lymphadenopathy, fever, weight loss and night sweats. It is a rare disease with worldwide distribution but commonly reported from Asia. It is diagnosed by excision biopsy of the lymph nodes. Clinical features suggest a viral aetiology though not proven. It is often misdiagnosed as either systemic lupus erythematosus or malignant lymphoma. Better understanding as well as high clinical suspicion would aid in the diagnosis of the disease. Treatment is mainly symptomatic, with non-steroidal analgesics and antipyretics. Corticosteroids are rarely indicated. Although patients show a spontaneous recovery in 1-4 months, a follow-up of several years would be required to study the development of SLE in these patients.
ISSN:0019-5847