Clinical Experience of Patients with Metastatic Gastric Cancer Treated Using Nab-PTX plus RAM chemotherapy

The present study reports the outcomes of chemotherapy using nab-PTXplus RAM in 6 patients with metastatic gastric cancer as recommended in the JGCA guidelines for special conditions. Four cases exhibited Grade 3 neutropenia, 1 exhibited Grade 3 hypertension, and no case developed febrile neutropeni...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 46; no. 7; p. 1195
Main Authors Kuga, Takayuki, Yano, Yuka, Tanaka, Yuuya, Sano, Fumiho, Inokuchi, Toshihiro, Nakamura, Takashi
Format Journal Article
LanguageJapanese
Published Japan 01.07.2019
Subjects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Humans
Neutropenia
Paclitaxel
Splenic Neoplasms
Stomach Neoplasms - drug therapy
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Summary:The present study reports the outcomes of chemotherapy using nab-PTXplus RAM in 6 patients with metastatic gastric cancer as recommended in the JGCA guidelines for special conditions. Four cases exhibited Grade 3 neutropenia, 1 exhibited Grade 3 hypertension, and no case developed febrile neutropenia; however, the adverse events were tolerated. One case showed partial response, 1 showed stable disease, 2 cases showed non-complete response/non-progressive disease, and 2 cases could not be evaluated. These results suggest that this treatment may be performed safely in ambulatory patients.
ISSN:0385-0684