D(1)-dopamine receptor is involved in the modulation of the respiratory rhythmical discharge activity in the medulla oblongata slice preparation of neonatal rats in vitro.

• Published in: Sheng li hsüeh pao Vol. 60; no. 6; p. 704
• Main Authors: Jiao, Yong-Gang, Wu, Zhong-Hai
• Format: Journal Article
• Language: Chinese
• Published: China 25.12.2008
• Subjects: Animals; Animals, Newborn; Benzazepines - pharmacology; Biological Clocks; Chromans - pharmacology; Female; In Vitro Techniques; Male; Medulla Oblongata - physiology; Rats; Rats, Sprague-Dawley; Receptors, Dopamine - physiology; Respiration

To explore the role of D(1)-dopamine receptor in the modulation of basic respiratory rhythm, neonatal (0-3 d) Sprague-Dawley rats of either sex were used. The medulla oblongata slice was prepared and the surgical procedure was performed in the modified Kreb's solution (MKS) with continuous vent...