Relations between fasting serum lipids and high-sensitivity C-reactive protein level in Chengdu residents

• Published in: Zhōnghuá xīnxuèguănbìng zázhì Vol. 40; no. 2; p. 125
• Main Authors: Shu, Yan, He, Sen, Chen, Xiao-ping, Lü, Zheng-bing, Yang, Rui, Liu, Kai, Cui, Kai-jun, Huang, De-jia
• Format: Journal Article
• Language: Chinese
• Published: China 01.02.2012
• Subjects: Aged; Alcohol Drinking; C-Reactive Protein - analysis; Cardiovascular Diseases - blood; Cardiovascular Diseases - epidemiology; China - epidemiology; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Dyslipidemias - epidemiology; Female; Humans; Inflammation; Male; Middle Aged; Smoking; Triglycerides - blood; China
• ISSN: 0253-3758
• DOI: 10.3760/cma.j.issn.0253-3758.2012.02.010

To explore the associations between fasting serum lipids and high-sensitivity C-reactive protein (hsCRP). Serum triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and hsCRP were measured in residents of Chengdu, China. Subjects with potential factors which might influence lipids and hsCRP were excluded, 580 subjects [mean age (62.3 ± 6.6) years; male: 58.7%] were finally recruited by random sampling methods. There was a weak positive relationship between TG and hsCRP (r = 0.108, P = 0.01) and a weak negative relationship between HDL-C and hsCRP (r = -0.197, P < 0.001), this was also true in the sub-group with BMI < 24 kg/m(2) (r = 0.236, -0.140 respectively, all P < 0.001). In subjects with BMI < 24 kg/m(2), the hsCRP concentration was significantly higher in subjects with higher TG or lower HDL-C (all P < 0.05). hsCRP increased in proportion with the degree of dyslipidemia. After adjusting for gender, age, TC, LDL-C, fasting blood glucose, systolic blood pressure, diastolic blood pressure, histo