A case of advanced esophageal cancer with no recurrence treated biweekly with postoperative docetaxel/nedaplatin combined chemotherapy after non-curative surgery

• Published in: Gan to kagaku ryoho Vol. 37; no. 6; p. 1101
• Main Authors: Sugimoto, Katsumi, Sasaki, Kensyuu, Karaki, Hirokazu, Okaya, Tomohisa, Suzuki, Hirofumi, Hayashi, Shinniti, Yamamoto, Kazuo, Yamamori, Hideo, Sugano, Isamu
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.06.2010
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Combined Modality Therapy; Esophageal Neoplasms - drug therapy; Esophageal Neoplasms - pathology; Esophageal Neoplasms - surgery; Female; Humans; Neoplasm Staging; Organoplatinum Compounds - administration & dosage; Organoplatinum Compounds - therapeutic use; Remission Induction; Taxoids - administration & dosage; Taxoids - therapeutic use
• ISSN: 0385-0684

We report a case of non-curatively resected esophageal cancer with no recurrence biweekly treated with postoperative docetaxel/nedaplatin combined chemotherapy. A 59-year-old woman underwent non-curative resection with esophagectomy for advanced esophageal cancer with direct invasion to the descending aorta in August, 2007. Postoperatively, she was treated biweekly with docetaxel/nedaplatin combined chemotherapy 32 times. In this period, there was no finding in the enhanced CTs, and clinically she was free from recurrence. The quality of life of this patient was also good. Thus, postoperative biweekly docetaxel/nedaplatin combined chemotherapy could be effective for advanced esophageal cancer after non-curative surgery and might be promising for long-term survival. This combined chemotherapy could be carried out on an outpatient basis, and the quality of life could also be preserved. More experience must be accumulated using this chemotherapy.