Effectiveness on post-exposure vaccination of varicella and its influencing factors in elementary schools in Beijing

• Published in: Zhōnghuá liúxíngbìng zázhì Vol. 30; no. 6; p. 559
• Main Authors: Ma, Rui, Sun, Mei-Ping, Sun, Mu, Hou, Wen-Juln, Jiang, Gui-Ying, Peng, Xing-Hui, Wu, Jiang
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2009
• Subjects: Chickenpox - epidemiology; Chickenpox - prevention & control; Chickenpox Vaccine - administration & dosage; Child; China - epidemiology; Humans; Patient Isolation; Post-Exposure Prophylaxis; Prospective Studies; School Health Services; Treatment Outcome; China
• ISSN: 0254-6450

To evaluate the effectiveness of post-exposure varicella vaccination in elementary schools in Beijing and to explore its influencing factors. From May to July 2007, varicella cases from 49 elementary schools in 4 districts in Beijing were observed prospectively. The study included 7882 children who were from the same classrooms, same floor or same bungalow areas with the varicella cases. Vaccination status, history on varicella and onset of rashes were collected to calculate the secondary attack rate among those children under observation and then the effectiveness of vaccine was calculated. The protection rate on post-exposure vaccination among children under observation was 85.26%. The rates were higher when the 1st case had received varicella vaccine before the onset, vaccines were administered soon after the exposure or there were less varicella cases occurred in the schools. For children in the same class, same floor or bungalow with varicella cases before post-exposure vaccination, the average rates of