The glycemic control and temporal characteristics of diabetes as risk factors for the occurence of diabetic renal disease

Diabetes is one of the most spread pandemy, which affects nowadays the world, its incidence increasing globally. The chronic complications of diabetes are extremely important, out of which the diabetic kidney disease (DKD) being by far the most expensive and severe. On the basis of statistic studies...

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Published inRevista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi Vol. 113; no. 2; p. 363
Main Authors Panduru, N M, Chivu, Laura Ioana, Chivu, R D, Albu, D F, Bădărăru, Ioana Anca, Ion, Daniela Adriana
Format Journal Article
LanguageEnglish
Published Romania 01.04.2009
Subjects
Biomarkers - blood
Blood Glucose - metabolism
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - epidemiology
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - diagnosis
Diabetes Mellitus, Type 2 - epidemiology
Diabetic Nephropathies - blood
Diabetic Nephropathies - epidemiology
Diabetic Nephropathies - etiology
Global Health
Humans
Hyperglycemia - blood
Hyperglycemia - epidemiology
Hyperglycemia - etiology
Incidence
Prevalence
Risk Factors
Romania - epidemiology
Survival Rate
Time Factors
Romania
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Summary:Diabetes is one of the most spread pandemy, which affects nowadays the world, its incidence increasing globally. The chronic complications of diabetes are extremely important, out of which the diabetic kidney disease (DKD) being by far the most expensive and severe. On the basis of statistic studies, we tried to identify the risk factors within some epidemiological studies. The research started in two directions: the hypothesis of environmental factors and associated diseases and the hypothesis of genetic factors. In this article we are trying to assess the role of glycaemic control, age, total duration and post-pubertal duration of diabetes as risk factors for diabetic nephropathy. The glycaemic control proved to be an essential risk factor in developing microvascular complications and DKD, the "normal" glycaemia being the only limit below which there are no microvascular complications. We do not know for sure exactly the role played by the total duration of diabetes and age in developing the diabetic nephropathy as well as other microvascular complications. The age of onset and the post-pubertal duration seem to be better associated to the development of nephropathy, but the causality has not been demonstrated yet. These are a part of the 21 risk factors quoted in the speciality literature as influencing the occurrence of DKD.
ISSN:0048-7848