Urinary tract infections in the neonatal intensive care unit: clinical analysis of 229 cases

To study the clinical features, distribution of pathogens, drug susceptibility, and treatment effectiveness in neonates with urinary tract infection (UTI) and admitted to the neonatal intensive care unit (NICU). The clinical data of 229 neonates who developed UTI during their stay in the NICU were r...

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Bibliographic Details
Published inZhongguo dang dai er ke za zhi Vol. 14; no. 3; p. 177
Main Authors Han, Yu-Jie, Yu, Sheng-Lin, Tao, Yun-Zhen
Format Journal Article
LanguageChinese
Published China 01.03.2012
Subjects
Drug Resistance, Bacterial
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Microbial Sensitivity Tests
Retrospective Studies
Urinary Tract Infections - drug therapy
Urinary Tract Infections - microbiology
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Summary:To study the clinical features, distribution of pathogens, drug susceptibility, and treatment effectiveness in neonates with urinary tract infection (UTI) and admitted to the neonatal intensive care unit (NICU). The clinical data of 229 neonates who developed UTI during their stay in the NICU were retrospectively studied. The main clinical manifestations of these children included fever/irregular body temperature, refusing to milk feeding, jaundice, vomiting, diarrhea, poor weight gain, and lethargy. The top three pathogens were Escherichia coli, Enterococcus feces, and Klebsiella pneumoniae. Escherichia coli and Klebsiella pneumoniae were highly resistant to ampicillin and most cephalosporins (≥ 85%), and were highly sensitive to imipenem (100%), meropenem (100%), cefoperazone/sulbactam and piperacillin/tazobactam (>90%). Enterococcus feces were highly resistant to penicillin (100%), rifampicin (84%) and gentamicin (79%), but were sensitive to vancomycin. The clinical manifestations of neonatal UTI are often
ISSN:1008-8830