The morphological and immunohistochemical features and malignancy potential of a hyalinizing trabecular tumor of the thyroid

The paper considers the morphological features of a rare hyalinizing trabecular tumor of the thyroid, which is of follicular cell origin. The signs of invasive tumor growth into to the intrinsic capsule and its blood vessels were observed in 2 of 7 cases. There was a positive immunohistochemical rea...

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Bibliographic Details
Published inArkhiv patologii Vol. 71; no. 6; p. 36
Main Authors Abrosimov, A Iu, Dvinskikh, N Iu, Makanin, M A, mal'kov, P G, Grinevich, V N
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.11.2009
Subjects
Adult
Carcinoma, Medullary - blood supply
Carcinoma, Medullary - metabolism
Carcinoma, Medullary - pathology
Carcinoma, Papillary - blood supply
Carcinoma, Papillary - metabolism
Carcinoma, Papillary - pathology
Female
Humans
Immunohistochemistry
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Proteins - metabolism
Retrospective Studies
Thyroid Neoplasms - blood supply
Thyroid Neoplasms - metabolism
Thyroid Neoplasms - pathology
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Summary:The paper considers the morphological features of a rare hyalinizing trabecular tumor of the thyroid, which is of follicular cell origin. The signs of invasive tumor growth into to the intrinsic capsule and its blood vessels were observed in 2 of 7 cases. There was a positive immunohistochemical reaction of tumor cells with antibodies to thyroglobulin and neuron-specific enolase and a negative one to calcitonin, galectin 3, cytokeratin 19, and HBME-1. The differential diagnosis of a tumor and papillary and medullary carcinomas of the thyroid, as well as its malignancy potential are discussed in the paper.
ISSN:0004-1955