Prognosis and treatment of sudden sensorineural hearing loss with total and severe all frequency hearing loss

• Published in: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Vol. 42; no. 10; p. 726
• Main Authors: Xia, Rui-ming, Li, Hua-ting, Yu, Li-sheng
• Format: Journal Article
• Language: Chinese
• Published: China 01.10.2007
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Deafness - diagnosis; Deafness - drug therapy; Female; Hearing Loss, Sudden - diagnosis; Hearing Loss, Sudden - drug therapy; Humans; Male; Middle Aged; Panax notoginseng - chemistry; Phytotherapy; Prognosis; Saponins - therapeutic use; Steroids - therapeutic use; Treatment Outcome; Young Adult
• ISSN: 1673-0860

To evaluate the treatment and prognosis of sudden sensorineural hearing loss (SSHL) with total and severe all frequency hearing loss. Sixty-two patients diagnosed as SSHL (0.25, 0.5, 1, 2, 4 kHz pure tone average > or = 56 dB) were studied from January 2003 to October 2006, in which 18 of them were treated with Xueshuantong (Panax notoginseng saponins) while 19 of them treated with steroid and Xueshuantong, and 25 of them treated with steroid, DF-521 and Xueshuantong. The hearing improvement rate of the patients treated with Xueshuantong was 22.2% (4/18) while the patients treated with steroid and Xueshuantong was 57.9% (11/19) and the patients treated with steroid, DF-521 and Xueshuantong was 68.0% (17/25). The good improvement rate of the patients treated with Xueshuantong was 5.6% (1/18) while the patients treated with steroid and Xueshuantong was 36.8% (7/19) and the patients treated with steroid, DF-521 and Xueshuantong was 60.0% (15/25). Over hearing improvement was significantly better in patients trea