A case of liver metastasis from gastric cancer treated with stereotactic radiation therapy

We report a case of liver metastasis from gastric cancer that was effectively controlled with stereotactic radiation therapy (SRT). A 77-year-old man underwent total gastrectomy, splenectomy, cholecystectomy and D2 dissection in February 2007 for type 3 gastric cancer in the upper third area that wa...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 37; no. 12; p. 2499
Main Authors Kimura, Yutaka, Taniguchi, Hirokazu, Yano, Hiroshi, Miyazaki, Susumu, Nakamura, Hidetoshi, Danno, Katsuki, Kanoh, Toshiyuki, Ohnishi, Tadashi, Tono, Takeshi, Nakano, Yoshiaki, Kagawa, Kazufumi, Monden, Takushi, Imaoka, Shingi
Format Journal Article
LanguageJapanese
Published Japan 01.11.2010
Subjects
Adenocarcinoma - pathology
Adenocarcinoma - therapy
Aged
Humans
Liver Neoplasms - radiotherapy
Liver Neoplasms - secondary
Male
Peritoneal Neoplasms - secondary
Radiosurgery
Stomach Neoplasms - pathology
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Summary:We report a case of liver metastasis from gastric cancer that was effectively controlled with stereotactic radiation therapy (SRT). A 77-year-old man underwent total gastrectomy, splenectomy, cholecystectomy and D2 dissection in February 2007 for type 3 gastric cancer in the upper third area that was diagnosed well to moderately differentiated adenocarcinoma and Stage II (T3 (SE) N0 H0 P0 CY0 M0). He suffered from the liver and peritoneal metastases with ascites in December 2007, so S-1 was administered. Ascites was disappeared, but liver metastasis was enlarged. Therefore, SRT (total of 52.8 Gy per 4 fractions) was performed for the liver metastasis. A clear reduction in tumor size was noted and he was presently alive with no sign of recurrence after 2 years. Immediately after SRT, grade 3 neutropenia and grade 2 AST/ALT elevation were occurred. Grade 2 pneumothorax and pleural effusion were recognized in August 2009 as tardive adverse event. It is thought that SRT is one of effective treatments for liver metastasis from gastric cancer.
ISSN:0385-0684