Application of diffusion tensor imaging-based arcuate fasciculus tractography and intraoperative arcuate fasciculus navigation

• Published in: Zhōngguó yīxué kēxuéyuàn xuébào Vol. 33; no. 5; p. 499
• Main Authors: Zhao, Yan, Chen, Xiao-Lei, Wang, Fei, Sun, Guo-Chen, Wang, Yu-Bo, Song, Zhi-Jun, Xu, Bai-Nan
• Format: Journal Article
• Language: Chinese
• Published: China 01.10.2011
• Subjects: Adult; Aged; Brain Neoplasms - surgery; Diffusion Magnetic Resonance Imaging - methods; Diffusion Tensor Imaging; Female; Follow-Up Studies; Humans; Male; Middle Aged; Monitoring, Intraoperative - methods; Neuronavigation - methods; Young Adult
• ISSN: 1000-503X
• DOI: 10.3881/j.issn.1000-503X.2011.05.005

To investigate the feasibility of applying diffusion tensor imaging (DTI)-based arcuate fasciculus tractography and intraoperative arcuate fasciculus navigation for neurosurgery. Totally 85 patients with interhemispheric tumors who had undergone intra-operative magnetic resonance imaging (MRI) and neuronavigation were divided into sinistrocerebral tumor (SCT) group (n = 55) and sham group (n = 30). All patients accepted routine MRI and DTI preoperatively. The results from both DTI-based arcuate fasciculus tractography and neuronavigation were applied to guide the surgery. All patients were followed up at 2-4 weeks and 3-6 months postoperatively. All patients smoothly received the pre-operative DTI-based arcuate fasciculus tractography. The three dimensional arcuate fasciculus was successfully integrated with the neuronavigation and achieved microscope heads-up display. Long-term follow-up showed that there were only 4 patients suffered from persistent language dysfunction. The combined application of DTI-base