A case of sigmoid colon carcinoma accompanied with hydronephrosis caused by peritoneal dissemination and para-aortic lymph node metastases markedly responded to chemotherapy

The patient was a 64-year-old male diagnosed as advanced sigmoid colon cancer accompanied with hydronephrosis caused by peritoneal dissemination and para-aortic lymph node metastases. We performed transverse colostomy in the end of June 2008. Though he got renal failure, he was recovered by dialysis...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 36; no. 12; p. 2213
Main Authors Hasegawa, Kumi, Matsumoto, Rikio, Yamada, Hirofumi, Kuroda, Toru, Mamiya, Yutaka, Kon, Akira
Format Journal Article
LanguageJapanese
Published Japan 01.11.2009
Subjects
Angiogenesis Inhibitors - administration & dosage
Antibodies, Monoclonal - administration & dosage
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Aorta, Abdominal
Bevacizumab
Colostomy
Fluorouracil - administration & dosage
Humans
Hydronephrosis - etiology
Leucovorin - administration & dosage
Lymphatic Metastasis
Male
Middle Aged
Neoplasm Seeding
Organoplatinum Compounds - administration & dosage
Peritoneal Cavity
Sigmoid Neoplasms - drug therapy
Sigmoid Neoplasms - pathology
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Summary:The patient was a 64-year-old male diagnosed as advanced sigmoid colon cancer accompanied with hydronephrosis caused by peritoneal dissemination and para-aortic lymph node metastases. We performed transverse colostomy in the end of June 2008. Though he got renal failure, he was recovered by dialysis and diuretic. He received chemotherapy with LV+5-FU in the middle of August, continuously with bevacizumab (BV)+mFOLFOX6 in the end of October. In December, an elevated CEA marker was decreased after these treatments. Sigmoidectomy was done in the beginning of February 2009, dissemination disappeared completely. Histologically, most mucinous carcinoma cells disappeared or denatured, with viable tumor cells slightly remained.
ISSN:0385-0684