Clinical observation of polypoidal choroidal vasculopathy

• Published in: Chung-hua yen k'o tsa chih Vol. 47; no. 1; p. 39
• Main Authors: Zou, Wen-Jun, Wen, Feng, Wu, Zhi-Feng, Huang, Shi-Zhou, Zhang, Jie, Luo, Guang-Wei
• Format: Journal Article
• Language: Chinese
• Published: China 01.01.2011
• Subjects: Aged; Aged, 80 and over; Choroid Diseases - diagnosis; Female; Fluorescein Angiography; Follow-Up Studies; Humans; Male; Middle Aged; Peripheral Vascular Diseases - diagnosis; Photochemotherapy; Pigment Epithelium of Eye - pathology; Prognosis; Retrospective Studies; Visual Acuity
• ISSN: 0412-4081
• DOI: 10.3760/cma.j.issn.04124081.2011.01.010

To observe the natural course and evaluate the prognostic factors influencing the follow-up visual acuity of polypoidal choroidal vasculopathy (PCV). It was a retrospective case series. Forty-five consecutive patients (51 eyes) who were diagnosed with PCV by fundus photography, fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) were followed up with (11.1 ± 2.0) months (mean ± SD). Age, baseline visual acuity, the presence of pigment epithelium detachment (PED), lesion size, the polypoidal lesions involving the fovea and the regression of polypoidal lesions were recorded. Multi-factor regression analysis of visual acuity at follow up was applied with SPSS 16.0 statistics software. Among the 45 patients (51 eyes), the hemorrhage or exudation were increased in 15 eyes (29.4%), decreased in 25 eyes (49.0%), 5 eyes (9.8%) developed macula scar and 6 eyes (11.8%) macula atrophy. During the follow-up period, the visual acuity was improved in 11 eyes (21.6%), stable in 21 (41.2%) and regre