Investigation on one vaccine-derived poliovirus (VDPV) case in Yunnan Province

To find out epidemiological feature of paralytic cases caused by type 2 vaccine-derived poliovirus (VDPV) and the excretion status of the case and to explore the enterovirus infection status among healthy children under five years old around the case in Zhaotong city, Yunnan Province in 2010. Field...

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Bibliographic Details
Published inBingdu xuebao Vol. 27; no. 3; p. 283
Main Authors Tang, Jing-Jing, Tian, Bing-Jun, Luo, Mei, Zhang, Jie, Kang, Wen-Yu, Yu, Wen, Ding, Zheng-Rong
Format Journal Article
LanguageChinese
Published China 01.05.2011
Subjects
Child, Preschool
China - epidemiology
Female
Humans
Infant
Male
Phylogeny
Poliomyelitis - epidemiology
Poliomyelitis - etiology
Poliovirus - classification
Poliovirus - isolation & purification
Poliovirus Vaccines - adverse effects
China
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Summary:To find out epidemiological feature of paralytic cases caused by type 2 vaccine-derived poliovirus (VDPV) and the excretion status of the case and to explore the enterovirus infection status among healthy children under five years old around the case in Zhaotong city, Yunnan Province in 2010. Field epidemiological studies at the epidemic area were conducted and a total of 108 stool samples were collected, three from the case, seven from the close contacts and 98 from the healthy children. VDPV was not isolated again from the case; Sabin-like PV strains or VDPV were not isolated from the close contacts and the healthy children; An active search for acute flaccid paralysis cases was conducted in the area, which indicated that the VDPV did not cause virus circulation in local area. Twenty one (20.0%) NPEVs were isolated from 105 stool samples. Among the 21 NPEV isolates, 11 isolates (52.4%) were HEV-A (3 serotypes), 10 isolates (47.6%) were HEV-B (4 serotypes).
ISSN:1000-8721