Effects of jingtian tongmai recipe on atherosclerotic plaque in rabbits

To evaluate the inhibiting effects of Jingtian Tongmai Recipe (JTTMR) in different dosages on atherosclerotic plaque using the arteriosclerosis rabbit model induced by high cholesterol diet supplemented with immunological injury. Fifty-four healthy New Zealand rabbits were randomly divided into six...

Full description

Saved in:
Bibliographic Details
Published inZhongguo Zhong xi yi jie he za zhi Vol. 29; no. 2; p. 136
Main Authors Zhao, Cui-Xia, Kasimu, Rena, Wang, Xiao-Mei
Format Journal Article
LanguageChinese
Published China 01.02.2009
Subjects
Animals
Aorta - pathology
Arteriosclerosis - drug therapy
Arteriosclerosis - pathology
C-Reactive Protein - metabolism
Drugs, Chinese Herbal - therapeutic use
Female
Lipids - blood
Male
Phytotherapy
Rabbits
Random Allocation
Online AccessGet more information

Cover

More Information
Summary:To evaluate the inhibiting effects of Jingtian Tongmai Recipe (JTTMR) in different dosages on atherosclerotic plaque using the arteriosclerosis rabbit model induced by high cholesterol diet supplemented with immunological injury. Fifty-four healthy New Zealand rabbits were randomly divided into six groups: the normal control group, the model group, the Xuezhikang (XZK) treated group and the three JTTMR treated groups treated respectively with low (1.29 g/kg/day), medium (2.57 g/kg/day) and high (5.14 g/kg/day) dosage of JTTMR. Indexes including serum lipids, C-reactive protein (CRP), and area ratio of aortic plaque/intima (PIR), and intima-media thickness ratio (IMT) were examined. Comparison of blood lipids showed that serum levels of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) were higher significantly in the model group than in the normal group (P<0.05); TC and LDL-C were lower in the XZK group and the JTTMR groups than in the model group (P<0.05); and these in
ISSN:1003-5370