The influence of lymph nodes detection on pathological staging in rectal cancer

To investigate the influence of lymph nodes detection on the pathological staging in rectal cancer specimens. From January 2007 to June 2008, 75 patients with rectal cancer who underwent total mesorectal excision were randomly divided into two groups: conventional group (n = 39), in which lymph node...

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Published inChung-hua wai kʿo tsa chih Vol. 48; no. 11; p. 816
Main Authors Lai, Dong-ming, Li, Ying-ru, Yang, Bin, Zhang, Yu-chao, Zhou, Jun, Chen, Shuang
Format Journal Article
LanguageChinese
Published China 01.06.2010
Subjects
Adult
Aged
Female
Humans
Lymph Nodes - pathology
Lymph Nodes - surgery
Lymphatic Metastasis - pathology
Male
Middle Aged
Neoplasm Staging
Rectal Neoplasms - pathology
Rectal Neoplasms - surgery
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Summary:To investigate the influence of lymph nodes detection on the pathological staging in rectal cancer specimens. From January 2007 to June 2008, 75 patients with rectal cancer who underwent total mesorectal excision were randomly divided into two groups: conventional group (n = 39), in which lymph nodes were detected by sight and palpation; fat clearance group (n = 36), in which lymph nodes were harvested after the specimens immersed in a fat clearance solution for 24 hours. The lymph node number harvested was compared between the two groups, and metastasis of the lymph nodes and its impact on the pathologic staging was analyzed in the two groups. A total of 75 patients (42 male and 33 female, the average age was 53.2 years) were enrolled in this study. In the conventional group, a mean of 14.4 lymph nodes (range, 8 - 27) was detected, and was significantly less than that in fat clearance group (mean 36.2, range, 18 - 62) (t = 5.800, P < 0.05). The tumor invasion was classified as T1 in 4 cases and 5 cases, T2 i
ISSN:0529-5815