Occupational exposure induced human transmissible highly pathogenic H5N1 avian influenza in one patient

• Published in: Zhonghua laodong weisheng zhiyebing zazhi Vol. 25; no. 3; p. 129
• Main Authors: Zhou, Hong-sheng, Liu, Jing-hu, Wang, Xiu-quan, Guo, Jiang-hua, Song, Xiao-lin
• Format: Journal Article
• Language: Chinese
• Published: China 01.03.2007
• Subjects: Adult; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human - diagnosis; Influenza, Human - etiology; Influenza, Human - therapy; Male; Occupational Exposure - adverse effects
• ISSN: 1001-9391

To describe the clinical manifestations and lung imaging characteristics of the human transmissible highly pathogenic H5N1 avian influenza. The clinical manifestations and lung imaging characteristics of human transmissible highly pathogenic H5N1 avian influenza in one patient were reviewed and analyzed. The patient had the clear history of occupational exposure. The fever and symptoms of influenza were prominent at onset and associated with the symptoms of the digestive tract. The laboratory findings comprised the significant decrease of the white blood cell count and the lymphocyte number and the impairment of the liver function and the myocardial enzymes. The disease progressed rapidly and multiple organs including lung, heart, liver and kidneys were involved. It was ineffective to administer anti-fungal, anti-virus and anti-inflammation medicines. It was in vain to use mechanical ventilation and pneumothorax intubation and closed drainage as well as the support therapy. In the X-ray film, the lesions prog