The assessment of chemoradiation therapy with CDDP/S-1 for advanced gastric cancer that was actively bleeding

In the management of inoperable patients with advanced gastric cancer, it is important to control a tumor bleeding actively and to make sure that the patient can take meals through the stenotic cardia for the purpose of keeping the patients' quality of life well. We treated five gastric cancer...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 37; no. 12; p. 2502
Main Authors Doi, Koichi, Ogata, Ken-ichi, Hirano, Yuichi, Kudo, Keisuke, Narita, Yasuko, Ohchi, Tetsufumi
Format Journal Article
LanguageJapanese
Published Japan 01.11.2010
Subjects
Aged
Aged, 80 and over
Antimetabolites, Antineoplastic - administration & dosage
Antineoplastic Agents - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Cisplatin - administration & dosage
Combined Modality Therapy
Drug Combinations
Female
Gastrointestinal Hemorrhage - etiology
Humans
Male
Middle Aged
Oxonic Acid - administration & dosage
Stomach Neoplasms - therapy
Tegafur - administration & dosage
Treatment Outcome
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Summary:In the management of inoperable patients with advanced gastric cancer, it is important to control a tumor bleeding actively and to make sure that the patient can take meals through the stenotic cardia for the purpose of keeping the patients' quality of life well. We treated five gastric cancer patients with chemoradiation therapy consisting of CDDP (6 mg/m2) and S-1 (100 mg/body). In the treatment results, we have never seen an active tumor bleeding and anemic state, which required a blood transfusion after the treatment. In all of the 5 cases, a total quantity of taking meals increased due to a cardia stenosis improvement by tumor. We thought this treatment was useful for patients with cardia stenosis and actively bleeding in advanced gastric cancer.
ISSN:0385-0684