Impact of diabetes mellitus on clinicopathological factors and prognosis of patients with colorectal cancer.

To analyze the impact of diabetes mellitus on the clinicopathological factors and prognosis of patients with colorectal cancer. A total of 599 patients with colorectal cancer treated between January 2000 and June 2007 were collected retrospectively. The patients were divided into diabetes mellitus (...

Full description

Saved in:
Bibliographic Details
Published inChung-hua wai kʿo tsa chih Vol. 48; no. 2; p. 88
Main Authors Gao, Rui-zhong, Gu, Jin, Du, Chang-zheng, Li, Ming
Format Journal Article
LanguageChinese
Published China 15.01.2010
Subjects
Adult
Aged
Aged, 80 and over
Colorectal Neoplasms - complications
Colorectal Neoplasms - pathology
Diabetes Mellitus
Female
Follow-Up Studies
Humans
Logistic Models
Male
Middle Aged
Prognosis
Retrospective Studies
Online AccessGet more information

Cover

More Information
Summary:To analyze the impact of diabetes mellitus on the clinicopathological factors and prognosis of patients with colorectal cancer. A total of 599 patients with colorectal cancer treated between January 2000 and June 2007 were collected retrospectively. The patients were divided into diabetes mellitus (DM) group and non-diabetes mellitus (NDM) group. The pathologic factors data was compared between the two groups, and the Logistic multivariable analysis was performed. The Cox regression model analysis of prognosis data was applied in 402 patients who underwent radical surgery without preoperative neoadjuvant therapy. A total of 58 cases (9.7%) developed diabetes mellitus. Significant differences was found in the body-weight, age, hypertension between the two groups (P < 0.05), while no significant differences in the pathologic factors, such as tumor differentiation, invasion depth, lymph node involvement, TNM stage and lymphovascular invasion was found between the two groups (P > 0.05). There was no significant c
ISSN:0529-5815