Oral paroxetine for premature ejaculation: a randomized controlled study

To validate the therapeutic efficacy of paroxetine in the treatment of premature ejaculation (PE). Eighty PE patients up to the inclusion criteria were equally randomized to an experimental and a control group. We observed all the patients for 4 weeks and recorded the baseline data on intravaginal e...

Full description

Saved in:
Bibliographic Details
Published inZhonghua nan ke xue Vol. 17; no. 10; p. 923
Main Authors Gong, Zhi-yong, Tang, Tie-long, Cui, Shu, Wang, Ji-zhong, Deng, Xian-zhong
Format Journal Article
LanguageChinese
Published China 01.10.2011
Subjects
Adult
Ejaculation
Humans
Male
Paroxetine - therapeutic use
Serotonin Uptake Inhibitors - therapeutic use
Sexual Dysfunction, Physiological - drug therapy
Treatment Outcome
Young Adult
Online AccessGet more information

Cover

More Information
Summary:To validate the therapeutic efficacy of paroxetine in the treatment of premature ejaculation (PE). Eighty PE patients up to the inclusion criteria were equally randomized to an experimental and a control group. We observed all the patients for 4 weeks and recorded the baseline data on intravaginal ejaculatory latency time (IELT) and sexual satisfaction scores, followed by oral medication of paroxetine at 20 mg/d for the patients in the experimental group and placebo for the controls. Thirty days after the treatment, we again recorded IELT and sexual satisfaction scores of the patients. After the treatment, the experimental group showed significantly prolonged IELT ([5.75 +/- 1.24] min) and increased sexual satisfaction score (6.4 +/- 1.2) as compared with the baseline data ([0.89 +/- 0.21] min and [2.7 +/- 0.9]) (P < 0.01). The control group exhibited no significant differences before and after the medication either in the mean IELT or in sexual satisfaction scores ([1.06 +/- 0.28] min vs [0.97 +/- 0.18] min
ISSN:1009-3591