HPV-associated oral warts

Human papillomavirus (HPV) is strictly epitheliotropic, infecting stratified squamous cutaneous and mucosal epithelial cells. Oral HPV infection may be subclinical or putatively associated with benign or malignant oral neoplasms. The benign HPV-associated oral lesions, focal epithelial hyperplasia (...

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Bibliographic Details
Published inSADJ (Houghton) Vol. 66; no. 2; p. 82
Main Authors Feller, L, Khammissa, R A G, Wood, N H, Marnewick, J C, Meyerov, R, Lemmer, J
Format Journal Article
LanguageEnglish
Published South Africa 01.03.2011
Subjects
AIDS-Related Opportunistic Infections - complications
AIDS-Related Opportunistic Infections - pathology
AIDS-Related Opportunistic Infections - virology
Focal Epithelial Hyperplasia - etiology
Focal Epithelial Hyperplasia - pathology
Focal Epithelial Hyperplasia - virology
HIV Seropositivity - complications
Humans
Mouth Diseases - etiology
Mouth Diseases - pathology
Mouth Diseases - virology
Papilloma - etiology
Papilloma - pathology
Warts - classification
Warts - etiology
Warts - pathology
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Summary:Human papillomavirus (HPV) is strictly epitheliotropic, infecting stratified squamous cutaneous and mucosal epithelial cells. Oral HPV infection may be subclinical or putatively associated with benign or malignant oral neoplasms. The benign HPV-associated oral lesions, focal epithelial hyperplasia (Heck disease), oral squamous cell papilloma, oral verruca vulgaris (common wart) and oral condyloma acuminatum, are collectively referred to as oral warts. Oral warts are usually asymptomatic, may be persistent or uncommonly, may regress spontaneously. HPV-associated oral warts have a prevalence of 0.5% in the general population, occur in up to 5% of HIV-seropositive subjects, and in up to 23% of HIV-seropositive subjects on highly active antiretroviral therapy. This paper is a clinico-pathological review of HPV-associated oral warts.
ISSN:1029-4864