Role of cytological test for cervices to identify human papillomavirus in the screening program on serious cervical lesion

• Published in: Zhōnghuá liúxíngbìng zázhì Vol. 30; no. 6; p. 626
• Main Authors: Wang, Guo-Ping, Li, Rui-Zhen, Wu, Lan-Na, Li, Juan, Liu, Zhi-Hong, Wang, Chun, Zhou, Yan-Qiu, Weng, Lei-Ming, Wu, Rui-Fang
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2009
• Subjects: Cervix Uteri - pathology; Cervix Uteri - virology; Cytodiagnosis - economics; Cytodiagnosis - methods; Early Detection of Cancer - methods; Female; Humans; Papanicolaou Test; Papillomaviridae - isolation & purification; Sensitivity and Specificity; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - virology; Vaginal Smears - economics; Vaginal Smears - methods
• ISSN: 0254-6450

To evaluate the value of cervical cytology and hybrid capture II (HC- II) human papillomavarus (HPV) test for screening cervical lesion. Conventional papanicolaou (Pap) smear by improved take-samples, liquid-based cytology test (LCT) and HC- II human papillomavarus test were performed in 425 women in Shang Mei-lin community of Futian region in Shenzhen city, from December 2007 to March 2008 and the above methods were performed in 75 women in Shenzhen Hospital of Peking University at the same time. Age stratified sampling was used. Samples of Pap were taken a broom-type sampling device (take-samples used for LCT) with split-sampling method. Those women with HPV-positive, Pap> or =atypical squamous cells of undetermined sign (ASCUS) or LCT> or =ASCUS received multi-spot biopsy and endocervical curettage under colposcopy. Final diagnosis would depend on pathological findings as well, to evaluate the values of Pap, LCT, HC-II HPV, Pap-HPV parallel test, LCT-HPV parallel test, Pap-HPV serial test and LCT-HPV seria