Analysis of treatment and prognosis of orbital adenoid cystic carcinoma

• Published in: Chung-hua yen k'o tsa chih Vol. 45; no. 4; p. 309
• Main Authors: Lin, Ting-ting, He, Yan-jin, Zhang, Hong, Song, Guo-xiang, Tang, Dong-run, Zhao, Hui-fen
• Format: Journal Article
• Language: Chinese
• Published: China 01.04.2009
• Subjects: Adolescent; Adult; Aged; Carcinoma, Adenoid Cystic - mortality; Carcinoma, Adenoid Cystic - therapy; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Orbital Neoplasms - mortality; Orbital Neoplasms - therapy; Prognosis; Retrospective Studies; Survival Rate; Young Adult
• ISSN: 0412-4081
• DOI: 10.3760/cma.j.issn.0412-4081.2009.04.005

To summarize the treatment outcomes of orbital adenoid cystic carcinoma and to evaluate prognostic factors. A retrospective case series study was performed on 75 patients with orbital adenoid cystic carcinoma treated from 1991 to 2006. The 2- and 5-year local recurrence rate of solid type orbital adenoid cystic carcinoma was significantly higher than that of the adeno-tubiform type [2-year, 85% (17/20) vs 23.53% (8/34), chi(2) = 19.14, P = 0.000; 5-year, 100% (19/19) vs 64.52% (20/31), Fisher's exact test, P = 0.003]. The regional extension and distant metastasis of solid type were more than those of adeno-tubiform type. The 5-year local recurrence rate treated by postoperative radiation was lower than that treated with only surgical excision [70% (14/20) vs 92.86% (13/14); Fisher's exact test, P = 0.198]. The 5-year local recurrence rate in patients initially treated by orbital evisceration during the first time was lower than that of cases which evisceration procedure was used after the recurrence [25% (1/4