Designer Natriuretic Peptides

Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that...

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Bibliographic Details
Published inJournal of investigative medicine Vol. 57; no. 1; pp. 18 - 21
Main Authors Lee, Candace Y. W., Lieu, Hsiao, Burnett, John C.
Format Journal Article
LanguageEnglish
Published 01.01.2009
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Summary:Designer natriuretic peptides (NPs) are novel hybrid peptides that are engineered from the native NPs through addition, deletion, or substitution of amino acid(s) with a goal toward optimization of pharmacological actions while minimizing undesirable effects. In this article, selected peptides that were designed in our laboratory are reviewed, and future directions for research and development of designer NPs are discussed.
ISSN:1081-5589
1708-8267
DOI:10.231/JIM.0b013e3181946fb2