The relationship between urinary albumin excretion and serum uric acid in general population

• Published in: Chung-hua nei kʿo tsa chih Vol. 50; no. 7; p. 550
• Main Authors: Fan, Xiao-hong, Cai, Jian-fang, Gao, Bi-xia, Mou, Li-jun, Li, Jin-hong, Liu, Xue-jiao, Wu, Jun-xue, Meng, Qing-yan, Wang, Hai-yun, Liu, Li-li, Li, Hang, Li, Xue-mei, Li, Xue-wang
• Format: Journal Article
• Language: Chinese
• Published: China 01.07.2011
• Subjects: Adult; Aged; Albuminuria - diagnosis; Albuminuria - epidemiology; Creatinine - blood; Female; Humans; Kidney Diseases - epidemiology; Kidney Diseases - metabolism; Lipids - blood; Logistic Models; Male; Metabolic Syndrome - epidemiology; Metabolic Syndrome - metabolism; Middle Aged; Prevalence; Risk Factors; Uric Acid - blood; Urinalysis
• ISSN: 0578-1426

To investigate the relationship between the urinary albumin excretion (UAE) and serum uric acid in general population. The study participants were derived from the epidemiological study on the association of metabolic syndrome and chronic kidney disease (CKD) in Pinggu district, Beijing. A total of 992 participants (463 men and 529 women) aged from 30 to 75 years were enrolled in this study. For each participant, UAE, serum uric acid, serum creatinine, and serum lipids were detected and other potential risk factors for CKD were surveyed. (1) The frequencies of microalbuminuria, macroalbuminuria and hyperuricemia were 12.9%, 1.8% and 4.3% respectively. The persons with hyperuricemia had significantly higher frequency of albuminuria than those without hyperuricemia (37.2% vs 13.7%, P < 0.01). (2) The participants were divided according to the quartiles (25%, 50%, 75%) of serum uric acid level, and the frequencies of albuminuria in males were 13.2%, 13.9%, 17.2% and 25.4%, while those in females were 8.4%, 6.2%,