Peroral endoscopic myotomy for esophageal achalasia: report of 42 cases

To evaluate the efficacy and the feasibility of peroral endoscopic myotomy (POEM) for esophageal achalasia (AC). The clinical data of 42 patients diagnosed as AC and received POEM in the Zhongshan Hospital of Fudan University between August 2010 and March 2011 were reviewed retrospectively. The key...

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Bibliographic Details
Published inZhonghua wei chang wai ke za zhi Vol. 14; no. 9; p. 705
Main Authors ZHOU, Ping-hong, CAI, Ming-yan, YAO, Li-qing, ZHONG, Yun-shi, REN, Zhong, XU, Mei-dong, CHEN, Wei-feng, QIN, Xin-yu
Format Journal Article
LanguageChinese
Published China 01.09.2011
Subjects
Adolescent
Adult
Aged
Cardia - physiopathology
Child
Deglutition Disorders - surgery
Esophageal Achalasia - surgery
Esophagoscopy
Female
Humans
Male
Middle Aged
Muscles - surgery
Retrospective Studies
Treatment Outcome
Young Adult
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Summary:To evaluate the efficacy and the feasibility of peroral endoscopic myotomy (POEM) for esophageal achalasia (AC). The clinical data of 42 patients diagnosed as AC and received POEM in the Zhongshan Hospital of Fudan University between August 2010 and March 2011 were reviewed retrospectively. The key procedures of POEM included esophageal mucosal incision, submucosal "tunneling" by endoscopic submucosal dissection(ESD) technique, endoscopic myotomy of the circular muscle, and closure of mucosal incision by hemostatic clips. The mean age of 42 cases was 43.9(range 10-70) years. The mean duration of disease was 8.7 years (range, 3 months to 50 years). The mean operative time was (68.5 ± 25.5) (range 23-180) minutes with a mean submucosal tunneling length of(10.5 ± 1.5)(range 8-15) cm. The average length of endoscopic myotomy of inner circular muscle was(9.5 ± 2.5)(range 7-13) cm. No serious complications related to POEM were encountered. The median follow-up period was 2.5(range 1-6) months. Dysphagia symptom was
ISSN:1671-0274