Long-term efficacy and safety research on functional dyspepsia treated with electroacupuncture and Zhizhu Kuanzhong capsule

• Published in: Zhōngguó zhēnjiǔ Vol. 31; no. 12; p. 1071
• Main Authors: Guo, Li-Ke, Zhang, Chao-Xian, Guo, Xiao-Feng
• Format: Journal Article
• Language: Chinese
• Published: China 01.12.2011
• Subjects: Adolescent; Adult; Capsules; Combined Modality Therapy; Drugs, Chinese Herbal - therapeutic use; Dyspepsia - blood; Dyspepsia - drug therapy; Dyspepsia - physiopathology; Dyspepsia - therapy; Electroacupuncture; Female; Gastric Emptying - drug effects; Humans; Male; Middle Aged; Motilin - blood; Treatment Outcome; Young Adult
• ISSN: 0255-2930

To observe the long-term efficacy and safety on functional dyspepsia treated with electroacupuncture and Zhizhu Kuanzhong capsule and explore the therapeutic mechanism. Three hundreds and twenty patients with confirmed diagnosis as functional dyspepsia were randomly divided into 4 groups: an electroacupuncture group, a Zhizhu Kuanzhong capsule group, a combined therapy group and a western medication group, 80 cases in each group. In electroacupuncture group, acupuncture was applied to Zusanli (ST 36), Zhongwan (CV 12), Neiguan (PC 6), Taichong (LR 3) and Gongsun (SP 4), twice per day, continuously for 5 days each week. In Zhizhu Kuanzhong capsule group, Zhizhu Kuanzhong capsule, 1.29 g was administered for oral application, three times each day. In combined therapy group, the therapeutic programs in the above-mentioned groups were applied in combination. In western medication group, Mosapride 5 mg, three times per day; Omeprazole 20 mg, twice per day and Amitriptyline 25 mg, twice per day were administered fo