Analysis of adverse events following 2009 influenza A (H1N1) vaccinoprophylaxis in Beijing

• Published in: Zhōnghuá yùfáng-yīxué zázhì Vol. 44; no. 10; p. 884
• Main Authors: Miao, Liang, Lu, Li, Wu, Jiang, Suo, Luo-dan, Liu, Dong-lei, Sun, Mei-ping, Pang, Xing-huo, Deng, Ying, Wang, Xiao-li
• Format: Journal Article
• Language: Chinese
• Published: China 01.10.2010
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; China - epidemiology; Female; Fever - chemically induced; Humans; Hypersensitivity - epidemiology; Immunization; Influenza A Virus, H1N1 Subtype; Influenza Vaccines - adverse effects; Influenza, Human - epidemiology; Influenza, Human - prevention & control; Male; Mass Vaccination; Middle Aged; Population Surveillance; Young Adult; China
• ISSN: 0253-9624

To evaluate the safety of 2009 influenza A (H1N1) vaccine based on mass immunization initiative in Beijing. There were 2 113 280 people were vaccinated during September to December 2009. The information of adverse events following immunization (AEFI) was collected through surveillance system, and descriptive methodology was used for data analysis. A Total of 612 AEFI cases were reported, among which there were 321 vaccine reaction cases following immunization, 203 coincidental illness cases, 82 psychogenic reaction cases, and 6 pending cases. The rates of rare reactions and common reactions associated with vaccination were respectively 5.54/100 000 (117/2 113 280) and 9.65/100 000 (204/2 113 280). The rate of serious rare reaction was 0.19/100 000 (4/2 113 280). The rates of vaccine reactions in urban, suburb and county were 16.87/100 000 (36/213 519), 17.81/100 000 (187/1 049 817) and 11.53/100 000 (98/849 944), respectively. The rates of rare reaction and common reaction in different age groups were between