The vascular endothelial function damage as well as early atherosclerosis in hypertensive youth

To explore young hypertensive people's vascular endothelial dysfunction and the early atherosclerosis changes. Rural youth subjects aged 20 to 35 in 6 villages were randomly selected from 20 villages of 3 townships, including Qili, Laojun and Shayan, in Hanzhong, Shanxi, China, from March to Ap...

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Bibliographic Details
Published inZhōnghuá yùfáng-yīxué zázhì Vol. 46; no. 1; p. 50
Main Authors Wang, Jing, Mu, Jian-jun, Ren, Jie, Liu, Wei-min, Fang, Yuan, Liu, Zhi-quan
Format Journal Article
LanguageChinese
Published China 01.01.2012
Subjects
Adult
Arteries - pathology
Atherosclerosis - pathology
Blood Pressure
Endothelium, Vascular - pathology
Female
Humans
Hypertension - pathology
Hypertension - physiopathology
Male
Risk Factors
Young Adult
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Summary:To explore young hypertensive people's vascular endothelial dysfunction and the early atherosclerosis changes. Rural youth subjects aged 20 to 35 in 6 villages were randomly selected from 20 villages of 3 townships, including Qili, Laojun and Shayan, in Hanzhong, Shanxi, China, from March to April of 2005, to survey their blood pressure and other related factors. 97 subjects with high blood pressure (hypertensive group) were detected while 400 with normal blood pressure (normal group). We measured their brachial artery flow-mediated vascular endothelial-dependent diastolic function (FMD) and the carotid intima-media thickness (IMT) by high resolution vascular ultrasound method, and other biochemical indexes. The body mass index (BMI) ((24.7 ± 4.3) kg/m²), waistline ((84.1 ± 11.7) cm), hipline ((92.5 ± 7.4) cm), TC ((4.6 ± 0.8) mmol/L), LDL-C ((2.8 ± 0.5) mmol/L), TG ((1.7 ± 1.1) mmol/L) and the blood insulin (INS) ((8.6 ± 4.4) mIu/L) were all significantly increased in young hypertensive group than those in n
ISSN:0253-9624