Lipid peroxidation and antioxidant system status in patients with acute myeloblast leukemia and toxic damage of the liver

• Published in: Likars'ka sprava no. 1-2; p. 55
• Main Authors: Kuzieva, G Z, Kholmatova, N M, Shevchenko, L I, Khuzhakhmedov, Zh D, Zavgorodniaia, S V
• Format: Journal Article
• Language: Russian
• Published: Ukraine 01.01.2009
• Subjects: Adult; Antioxidants - administration & dosage; Antioxidants - metabolism; Antioxidants - therapeutic use; Catalase - blood; Catalase - metabolism; Chemical and Drug Induced Liver Injury - drug therapy; Chemical and Drug Induced Liver Injury - enzymology; Chemical and Drug Induced Liver Injury - metabolism; Glutathione Peroxidase - blood; Glutathione Peroxidase - metabolism; Glutathione Reductase - blood; Glutathione Reductase - metabolism; Humans; Leukemia, Myeloid, Acute - drug therapy; Leukemia, Myeloid, Acute - enzymology; Leukemia, Myeloid, Acute - metabolism; Lipid Peroxidation - drug effects; Lipid Peroxides - blood; Lipid Peroxides - metabolism; Phospholipids - administration & dosage; Phospholipids - therapeutic use; S-Adenosylmethionine - administration & dosage; S-Adenosylmethionine - therapeutic use; Superoxide Dismutase - blood; Superoxide Dismutase - metabolism; Treatment Outcome
• ISSN: 1019-5297

Patients with acute myelogenous leucosis with toxic damage of the liver against polychemotherapy have an expressed disbalance in the lipid peroxidation-anti-oxidant system, which is possible to correct effectively using S-adenozilmetionin (heptral) was observed.