Evaluation on the visual inspection with Lugol's iodine in cervical cancer screening program

• Published in: Zhōnghuá liúxíngbìng zázhì Vol. 27; no. 1; p. 15
• Main Authors: Li, Ni, Ma, Cong-ping, Sun, Li-xin, Zhang, Yong-zhen, Shao, Shu-li, Xing, Ju-xia, Bao, Yan-ping, Huang, Rui-de, He, Li-ji, Qiao, You-lin
• Format: Journal Article
• Language: Chinese
• Published: China 01.01.2006
• Subjects: Adult; Cervical Intraepithelial Neoplasia - diagnosis; Cervical Intraepithelial Neoplasia - epidemiology; China - epidemiology; Early Detection of Cancer - economics; Early Detection of Cancer - methods; Female; Health Resources; Humans; Incidence; Iodides; Program Evaluation; Rural Health; Sensitivity and Specificity; Socioeconomic Factors; Uterine Cervical Neoplasms - diagnosis; Uterine Cervical Neoplasms - epidemiology; China
• ISSN: 0254-6450

To evaluate visual inspection with Lugol's iodine (VILI) in cervical cancer screening program and to provide evidence for designing a cervical cancer screening algorithm in high risk areas of existing low-resource settings to reduce the incidence and mortality of cervical cancer. Women in Yangcheng county, Shanxi province were screened with VILI, colposcopy, liquid-based cytology test and human papilloma virus (HPV) DNA test. The efficacy of different screening tests was compared by Youden's index based on the pathology as the gold standard. In the population being screened, the mean age was 40.80 +/- 10.75 years old. Based on pathological findings, 4.35% (32/735) of the subjects had >or= CIN (cervical intraepithelial neoplasia) II. The sensitivity and specificity for the VILI test (>or= positive) were 53.13 and 82.19, while 56.25 and 79.09 were for colposcopy (>or= low grade dysplasia) respectively. Comparing by the Youden's indexs, there was no statistically significant difference (P > 0.05) between VILI an