Measurement of grating acuity in guinea pigs by a customized automated optomotor device

The guinea pig becomes an important model for studies on myopia, but little is known about its visual performance. In this study, grating acuity was measured using a custom-built automated device to track optomotor responses. To record head nystagmus, guinea pigs were individually placed in the cent...

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Published inChung-hua yen k'o tsa chih Vol. 46; no. 8; p. 725
Main Authors Jiang, Li-qin, Zhang, Sen, Mo, Dan-ping, Ye, Ling-ying, Qu, Jia, Zhou, Xiang-tian
Format Journal Article
LanguageChinese
Published China 01.08.2010
Subjects
Animals
Equipment Design
Guinea Pigs
Myopia - physiopathology
Optometry - instrumentation
Optometry - methods
Refraction, Ocular
Visual Acuity
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Summary:The guinea pig becomes an important model for studies on myopia, but little is known about its visual performance. In this study, grating acuity was measured using a custom-built automated device to track optomotor responses. To record head nystagmus, guinea pigs were individually placed in the center of a rotating drum of 130 cm diameter. The drum was covered inside with square wave gratings of adjustable fundamental spatial frequencies and contrast. The turning movements of the head were tracked using custom-written video software that detected two little white spots painted on a small black piece of cardboard that was attached to the guinea pig's head. Angular head speed was determined from the positions of the two white spots with respect to each other over time, and the ratio of angular head speed to drum speed was determined (the "gain"). In 11 guinea pigs of the same age, but with different refractive states (+9.7 to -15.0 D), responses to spatial frequencies of 0.6 and 2.4 cyc/deg were tested. Further
ISSN:0412-4081
DOI:10.3760/cma.j.issn.0412-4081.2010.08.011