Clinical analyses of sudden sensorineural hearing loss in 14 nasopharyngeal carcinomas following radiotherapy

• Published in: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Vol. 46; no. 9; p. 705
• Main Authors: Chen, Ping, Tang, An-zhou, Zhang, Zhe, Yin, Shi-hua, Cai, Hong-wu, Fang, Qin, He, Guang-yao
• Format: Journal Article
• Language: Chinese
• Published: China 01.09.2011
• Subjects: Adult; Audiometry, Pure-Tone; Carcinoma; Female; Hearing Loss, Sensorineural - etiology; Hearing Loss, Sudden - etiology; Humans; Male; Middle Aged; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms - radiotherapy; Radiotherapy - adverse effects; Retrospective Studies
• ISSN: 1673-0860

To investigate the clinical characteristics and effects of sudden sensorineural hearing loss in nasopharyngeal carcinoma (NPC) following radiotherapy. The clinical characteristics and effects in 14 NPC patients (15 ears) with sudden sensorineural hearing loss following radiotherapy were retrospectively analyzed. The sudden sensorineural hearing loss happened more in male subjects than female subjects and more in the left ear than the right ear. Its occurrence time was averaged 6.6 years following radiotherapy. Most of the patients suffered hearing loss prior to the sudden sensorineural hearing loss. The 250, 500, 1000, 2000, 4000 Hz average hearing thresholds: sudden hearing loss ears (78.5 ± 24.7) dBHL, none-sudden hearing loss ears (57.0 ± 32.4) dBHL, among which, 73.33% (11/15) for sensorineural hearing loss, 26.67% (4/15) for mixed hearing loss. 12 cases had complications following radiotherapy. At least one case had posterior circulation barrier. The total effective rate was 26.67% (4/15) and four cases