Visualization of intimal proliferation of drug-eluting stent and bare mental stent by use of optical coherence tomography

• Published in: Zhong hua yi xue za zhi Vol. 86; no. 16; p. 1102
• Main Authors: Chen, Bu-xing, Ma, Feng-yun, Luo, Wei, Xie, Wen-li, Sun, Shu-hong, Guo, Xu-mei, Wang, Feng, Zhao, Xi-zhe, Chu, Xiao-wen
• Format: Journal Article
• Language: Chinese
• Published: China 25.04.2006
• Subjects: Adult; Aged; Coronary Disease - pathology; Coronary Disease - therapy; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Male; Metals; Middle Aged; Stents; Time Factors; Tomography, Optical Coherence - methods; Treatment Outcome; Tunica Intima - pathology
• ISSN: 0376-2491

To compare neointimal proliferation of drug-eluting stent (DES) with bare mental stent (BMS) by optical coherence tomography (OCT). OCT images were obtained in 21 diseased coronary vessels with 23 stents in 19 patients with coronary artery disease at 5 - 93 months post DES or BMS stents. Twenty-two stents of all 23 stents were divided into three groups. Nine DES stents at 6 - 10 months post stenting were considered as group A, 8 BMS stents at 5 - 10 months post stenting as group B, and 5 BMS stents at 23 - 93 months post stenting as group C. OCT images were quantitatively analyzed to compare neointimal proliferation of three groups after stenting. All 21 vessels and 23 stents OCT images were successfully acquired. The maximal neointima, luminal loss in diameter and cross sectional area (CSA), and restenosis in diameter and CSA were significantly statistically different within three groups. The maximal intimal proliferations post stenting in group A were significantly lower than group B (0.20 mm +/- 0.13 mm vs