Analysis of auditory steady-state response to multiple simultaneous stimuli and cochlea morphology in guinea pigs with posterior semicircular canal fistula

To observe the changes of auditory steady-state response (ASSR) threshold in guinea pigs with posterior semicircular canal fistula. In 10 guinea pigs, a window was opened in the posterior semicircular canal of the left ear with the right ear serving as the control for testing the ASSR under anesthes...

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Published inNan fang yi ke da xue xue bao = Journal of Southern Medical University Vol. 26; no. 4; p. 495
Main Authors Xie, Nan-ping, Chen, Guo-qiang, Yang, Xing, Shu, Si-yun
Format Journal Article
LanguageChinese
Published China 01.04.2006
Subjects
Animals
Audiometry, Pure-Tone - methods
Auditory Threshold - physiology
Cochlea - pathology
Evoked Potentials, Auditory
Fistula - pathology
Fistula - physiopathology
Guinea Pigs
Labyrinth Diseases - pathology
Labyrinth Diseases - physiopathology
Semicircular Canals
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Summary:To observe the changes of auditory steady-state response (ASSR) threshold in guinea pigs with posterior semicircular canal fistula. In 10 guinea pigs, a window was opened in the posterior semicircular canal of the left ear with the right ear serving as the control for testing the ASSR under anesthesia with pentobarbital sodium. The mean and standard deviation of ASSR threshold (dB SPL) at 0.5, 1, 2, and 4 kHz in the left ear was 35.00+/-14.33, 25.50+/-12.37, 20.00+/-9.37 and 20.00+/-9.18, respectively, and was 31.00+/-16.19, 25.50+/-12.34, 18.00+/-6.96 and 18.50+/-6.71 in the right ear, respectively. Paired-sample t test showed no significant difference in the ASSR at the same frequency between the two ears. Small fistula by surgery causes no significant hearing loss in guinea pigs.
ISSN:1673-4254