Effect of transcutaneous acupoint electrical stimulation on lipid peroxidation and cognitive function in patients experiencing craniotomy

To observe the effect of transcutaneous acupoint electrical stimulation (TAES) on serum superoxide dismutase (SOD) activity, malondialdehyde (MDA) and S100beta contents in craniotomy patients for studying its cerebral protection mechanism. Fifty patients scheduled for neurosurgery were randomly divi...

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Bibliographic Details
Published inZhēncì yánjiū Vol. 34; no. 1; p. 52
Main Authors Ni, Jian-wu, Meng, Yi-nan, Xiang, Hai-fei, Ren, Qiu-sheng, Wang, Jun-lu
Format Journal Article
LanguageChinese
Published China 01.02.2009
Subjects
Acupuncture Points
Adult
Aged
Craniotomy
Electric Stimulation Therapy
Female
Humans
Lipid Peroxidation
Male
Malondialdehyde - blood
Middle Aged
Skull - metabolism
Skull - surgery
Superoxide Dismutase - blood
Young Adult
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Summary:To observe the effect of transcutaneous acupoint electrical stimulation (TAES) on serum superoxide dismutase (SOD) activity, malondialdehyde (MDA) and S100beta contents in craniotomy patients for studying its cerebral protection mechanism. Fifty patients scheduled for neurosurgery were randomly divided into TAES group (n = 25) and control group (n=25) with randomized block method. For patients of TAES group, TAES was applied to bilateral Hegu (LI 4) and Quchi (LI 11), Zusanli (ST 36) and Sanyinjiao (SP 6) from 30 minutes on before anesthesia to the end of operation. Patients of control group were anesthetized with sevoflurane inhalation and intermittent (i.v.) of sulfenany and vecurnium bromide. Blood samples were taken for assaying serum SOD activity, MDA and S100beta contents with purinase oxydasis, biochemiluminescence and enzyme linked immunosorbent assay separately. Scores of cognitive ability were given by using Mini Mental State Examination (MMSE). In comparison with pre-anesthesia, serum SOD activity
ISSN:1000-0607