Localization and pathological examination of sentinel lymph node during operation in gastric cancer

To evaluate the application of sentinel lymph node (SLN) biopsy in diagnosis and treatment of gastric cancer. Thirty- eight patients with gastric cancer were divided into three groups (T(1); T(2); T(3)) according to tumor invasion depth. SLN was localized using methyl blue injection method. Metastat...

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Bibliographic Details
Published inZhonghua wei chang wai ke za zhi Vol. 8; no. 1; p. 29
Main Authors Fu, Xi-bo, Hu, Xiang
Format Journal Article
LanguageChinese
Published China 01.01.2005
Subjects
Adult
Aged
Female
Humans
Male
Methylene Blue
Middle Aged
Neoplasm Staging
Sentinel Lymph Node Biopsy
Stomach Neoplasms - diagnosis
Stomach Neoplasms - pathology
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Summary:To evaluate the application of sentinel lymph node (SLN) biopsy in diagnosis and treatment of gastric cancer. Thirty- eight patients with gastric cancer were divided into three groups (T(1); T(2); T(3)) according to tumor invasion depth. SLN was localized using methyl blue injection method. Metastatic lymph nodes were detected by immunohistochemical staining of cytokeratin (CK- 19). SLN(S ) were detected in all 38 patients and lymph node metastasis occurred in 18 cases. The sensitivity, false- negative rate, and diagnostic accuracy of SLN for lymph node metastasis were 83.3% 16.7% and 92.1% respectively. The diagnostic accuracy was 100% in T1 cases without false- negative cases, 94.1% in T(2) cases with one false- negative case, 75% in T(3) cases with two false- negative cases. The method of injecting methylene blue around the primary tumor is a feasible method that can determine SLN localization during operation.
ISSN:1671-0274