Harmful elements removal from Polygonum multiflorum by supercritical CO2 extraction
To remove harmful elements as copper, lead and arsenic from Polygonum multiflorum, a Chinese traditional medicine, by supercritical carbon dioxide extraction. With sodium diethyldithiocarbamate (NaDDC) as a chelating agent and ethanol as a modifier, the effects of extraction style, time, pressure, t...
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Published in | Zhong yao cai Vol. 31; no. 10; p. 1567 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
China
01.10.2008
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Subjects | |
Online Access | Get more information |
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Summary: | To remove harmful elements as copper, lead and arsenic from Polygonum multiflorum, a Chinese traditional medicine, by supercritical carbon dioxide extraction.
With sodium diethyldithiocarbamate (NaDDC) as a chelating agent and ethanol as a modifier, the effects of extraction style, time, pressure, temperature and amount of chelating agent on chelating extraction process were discussed.
The condition was optimized as following: 28 MP as extraction pressure, 60 degrees C as extraction temperature, 1 h as static extraction time, 2 h as dynamic extraction time, m(herb) : m(NaDDC) = 5 : 1, m(herb) : m(ethanol) = 1 : 1. Under this condition, the extraction rate of Cu, Pb and As were up to 60% which achieved US FDA standard, while the physioloically active substance of 2,3,5,4'-tetrahydroxy-silbene-2-O-beta-D-glucoside was not extracted.
The results show chelating extraction by supercritical CO2 can provide a non-destructive method to decrease the content of harmful elements from Chinese traditional medicines. |
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ISSN: | 1001-4454 |