Experimental study on effect of erzhi tiangui recipe on quality of oocyte in mice

To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation. Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Gro...

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Published inZhongguo Zhong xi yi jie he za zhi Vol. 24; no. 7; p. 625
Main Authors Lian, Fang, Sun, Zheng-gao, Zhang, Jian-wei, Zhang, Ning, Liu, Yanhe, Mu, Lin, Zhang, Peng
Format Journal Article
LanguageChinese
Published China 01.07.2004
Subjects
Animals
Cell Division - drug effects
Drug Synergism
Drugs, Chinese Herbal - pharmacology
Embryo Transfer
Female
Fertilization - drug effects
Fertilization in Vitro - drug effects
Menotropins - pharmacology
Mice
Oocytes - drug effects
Oocytes - physiology
Ovulation Induction
Random Allocation
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Summary:To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation. Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Group D with normal saline. Ovulation test and cleavage test were conducted to observe the effect of treatment on quality of oocytes. The difference on ovulation number between Group A and C was insignificant, but the difference in comparison between the two groups was significant in aspects of oocyte morphological scoring, fertilization rate and cleavage rate (P<0.05). ETR could play its effect synergistically with Western medicine, and raise the quality of oocytes.
ISSN:1003-5370