An analysis of antiretroviral therapy outcomes in the Medecins Sans Frontieres/Guangxi Center for Disease Control and Prevention HIV/AIDS project

• Published in: Chung-hua nei kʿo tsa chih Vol. 47; no. 3; p. 228
• Main Authors: Yang, Yu-Ning, Durier, Nicolas, Tang, Zhi-Rong
• Format: Journal Article
• Language: Chinese
• Published: China 01.03.2008
• Subjects: Acquired Immunodeficiency Syndrome - drug therapy; Acquired Immunodeficiency Syndrome - mortality; Acquired Immunodeficiency Syndrome - prevention & control; Adult; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Child, Preschool; China; Female; Follow-Up Studies; HIV Infections - drug therapy; HIV Infections - mortality; HIV Infections - prevention & control; Humans; Infant; Infant, Newborn; Male; Outcome Assessment (Health Care) - statistics & numerical data; Preventive Medicine - organization & administration; Preventive Medicine - statistics & numerical data; Retrospective Studies; Survival Rate; Time Factors; China
• ISSN: 0578-1426

To evaluate the 3-year outcomes of the Medecins Sans Frontieres/Guangxi Center for Disease Control and Prevention comprehensive and free of charge HIV/AIDS treatment and care project. We present a detailed retrospective analysis of treatment outcomes of 432 cases who received highly active antiretroviral therapy (HAART) from December 2003 to December 2006. Among the adult patients who received HAART, the mortality rate was 6.5% and only 12 (2.8%) patients were lost to follow up. The mean CD4+ T cell count increase was 147 cells/microl and 246 cells/microl for patients receiving HAART for 9-15 and 21-27 months respectively. An adherence assessment conducted during March to December 2006 indicated that 95.9% of the study cases reached an adherence of 95% or more of the prescribed medications. Among the 30 children patients who received HAART, 4 (13.3%) cases died and the mean CD4+ T cell increase after 9-15 and 21-27 months of HAART was 673 cells/microl and 658 cells/microl respectively. 148 of the adult patien