Clinical analysis of 48 patients with vaginal enlarged amputation of cervix

• Published in: Chung-hua fu chʿan kʿo tsa chih Vol. 43; no. 1; p. 41
• Main Authors: Zeng, Si-yuan, Li, Long-yu, Li, Cheng-xin, Shu, Kuan-yong, Pan, Mei, Li, Han-ping, Luo, Bing, An, Yun-ting, Liang, Mei-rong, Wu, Yun-yan
• Format: Journal Article
• Language: Chinese
• Published: China 01.01.2008
• Subjects: Adult; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - surgery; Cervical Intraepithelial Neoplasia - pathology; Cervical Intraepithelial Neoplasia - surgery; Cervix Uteri - pathology; Cervix Uteri - surgery; Female; Gynecologic Surgical Procedures - methods; Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Treatment Outcome; Uterine Cervical Neoplasms - pathology; Uterine Cervical Neoplasms - surgery
• ISSN: 0529-567X

To evaluate the feasibility and safety of vaginal enlarged amputation of cervix to treat patients with cervical cancer of stage Ia1 and cervical intraepithelial neoplasia grade III (CIN III) who were unfit for conization surgery. From July 2002 to May 2007, patients with cervical cancer at stage Ia1, diagnosed by pathology after loop electrosurgical excision procedure (LEEP), large area CIN III (the area of lesion>or=3/4 on colposcopy), CIN III coexisted with vaginal intraepithelial neoplasia (VAIN) in the superior segment of vagina, CIN II-III recurrence or with residual lesion, positive margin after conization of cervix, who wanted to preserve fertility and (or) corpus uteri were selected to receive vaginal enlarged amputation of cervix. Forty-eight cases including 5 with cervical cancer in stage Ia1, 38 with large area CIN III (9 with gland involvement), 2 with residual lesion and 2 with positive margin after LEEP, 1 recurrence after cold knife conization, received the procedure successfully. The median ag