A case of cardiac tamponade induced by gastric cancer responding to S-1

A 56-year-old man was admitted to our hospital for gastric cancer. He had dyspnea before admission. Chest CT scan showed massive pericardial and pleural effusion. He was treated by cardiac drainage, and cytology of the effusion showed class V. We injected mitomycin C 10 mg into the pericardiac cavit...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 36; no. 9; p. 1557
Main Authors Nakazaki, Takayuki, Hamasaki, Keiko, Shimizu, Kaori, Shindo, Hisakazu, Sano, Isao, Taniguchi, Hideki
Format Journal Article
LanguageJapanese
Published Japan 01.09.2009
Subjects
Antimetabolites, Antineoplastic - therapeutic use
Cardiac Tamponade - drug therapy
Cardiac Tamponade - etiology
Drug Combinations
Humans
Male
Middle Aged
Oxonic Acid - therapeutic use
Stomach Neoplasms - complications
Tegafur - therapeutic use
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Summary:A 56-year-old man was admitted to our hospital for gastric cancer. He had dyspnea before admission. Chest CT scan showed massive pericardial and pleural effusion. He was treated by cardiac drainage, and cytology of the effusion showed class V. We injected mitomycin C 10 mg into the pericardiac cavity, and also administered S-1 100 mg per day. His dyspnea improved and he was discharged. Afterward the dyspnea re-appeared, and he died 9 months after the diagnosis. We report this rare case of cardiac tamponade induced by gastric cancer responding to S-1 with a review of the literature.
ISSN:0385-0684