The oxygen-transport function of blood in reconstructive operations on the aorto-femoral segment and application of high molecular hydroxyethyl starch

• Published in: Vestnik hirurgii im. I.I. Grekova Vol. 164; no. 2; p. 55
• Main Authors: Naumenko, S E, Smyshliaeva, G V
• Format: Journal Article
• Language: Russian
• Published: Russia (Federation) 2005
• Subjects: Aged; Aorta, Abdominal - physiopathology; Aorta, Abdominal - surgery; Arteriosclerosis - metabolism; Arteriosclerosis - physiopathology; Arteriosclerosis - surgery; Female; Femoral Artery - physiopathology; Femoral Artery - surgery; Humans; Hydroxyethyl Starch Derivatives - therapeutic use; Lower Extremity - blood supply; Lower Extremity - physiopathology; Male; Middle Aged; Oxygen - blood; Plasma Substitutes - therapeutic use; Prospective Studies; Reconstructive Surgical Procedures - methods
• ISSN: 0042-4625

The prospective randomized investigation included 71 patients with obliterating atherosclerosis of the lower extremities with chronic ischemia. Planned operations of aorto-bifemoral shunts were made. Patients of the first group (n=43) were treated by infusion therapy including solutions of colloids and crystalloids. In the second group a solution of high molecular hydroxyethyl starch was used in addition to colloids and crystalloids. Transfusion of the allogenic components of blood was made in the both groups according to the indications. The parameters of the oxygen-transport function of blood were studied before initial narcosis, under conditions of general anesthesia before the beginning of operation, in 60 minutes of reperfusion after finishing the aorto-femoral shunting, and in a day after operation. It was shown that using the solution of high molecular hydroxyethyl starch promoted the elevated level of the delivery and consumption of oxygen as compared with the standard infusion-transfusion therapy which is explained by the predominantly hemodynamic component of the oxygen transport.