Effect of heparin on fetal growth restriction
To investigate the clinical effect and safety of heparin in treating fetal growth restriction (FGR). A total of 107 women diagnosed with FGR were randomized into three groups. Group 1 (standard heparin group, n = 37) received 50 - 75 mg standard heparin added to 500 ml 5% glucose sodium chloride, in...
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Published in | Chung-hua fu chʿan kʿo tsa chih Vol. 39; no. 12; p. 793 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
China
01.12.2004
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Subjects | |
Online Access | Get more information |
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Summary: | To investigate the clinical effect and safety of heparin in treating fetal growth restriction (FGR).
A total of 107 women diagnosed with FGR were randomized into three groups. Group 1 (standard heparin group, n = 37) received 50 - 75 mg standard heparin added to 500 ml 5% glucose sodium chloride, infused intravenously in 6 - 8 hours. Group 2 (low molecular weight heparin group, n = 31) received 0.2 - 0.4 ml low molecular weight heparin given by subcutaneous injection. Control group (n = 39) received 20 ml dan-shen added to 500 ml low-molecular-weight dextran infused intravenously. Fetal growth indices, biophysical score, umbilical artery blood flow, count of platelet (PLT), prothrombin time (PT), activated partial thromboplastin time (APTT), 1-minute Apgar score, body weight and gestational age of the neonates were measured. Babies prognosis was followed-up.
(1) Height of fundus of uterus was obviously increased per week in the groups of standard heparin (0.7 +/- 0.6) cm and low molecular weight heparin [(0.7 |
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ISSN: | 0529-567X |