Effect of gegen qinlian decoction combined with short-term intensive insulin treatment on patients with type 2 diabetes mellitus of dampness-heat syndrome

• Published in: Zhongguo Zhong xi yi jie he za zhi Vol. 26; no. 6; p. 514
• Main Authors: Zeng, Yi-peng, Huang, Yu-sheng, Hu, Yun-gang
• Format: Journal Article
• Language: Chinese
• Published: China 01.06.2006
• Subjects: Adult; Diabetes Mellitus, Type 2 - drug therapy; Diagnosis, Differential; Drug Therapy, Combination; Drugs, Chinese Herbal - therapeutic use; Female; Humans; Insulin - therapeutic use; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy
• ISSN: 1003-5370

To observe the effect of Gegen Qinlian Decoction (GQD) in combination with short-term intensive insulin treatment on type 2 diabetes mellitus (T2DM) of dampness-heat syndrome and its influence on dosage of insulin used. The GQD group (n = 14) was treated by GQD and insulin, while the conventional group (n = 16) was given insulin intensive treatment alone. In the GQD group, the treatment was markedly effective in 5 patients, effective in 6 and ineffective in 3, the total effective rate being 78.6%, much better than that in the conventional group (2, 7, 7 and 56.3% respectively, u = 2.58, P < 0.01). And it took less time for controlling blood glucose (BG) in the GQD group (4.54 +/- 0.50 days) than that in the conventional group (5.31 +/- 0.57 days, P <0.01); furthermore, by the end of the treatment course, as compared with that at the time just after BG being controlled, the daily average insulin dosage used in the GQD group reduced by 9.07 +/- 6.51 U, while it was only 4.38 +/- 5.94 U in the conventional group