Evaluation of measurement uncertainty for the determination of ginsenosides in Radix ginseng by HPLC

To set out the procedure for estimation of measurement uncertainty for the determination of ginsenosides R(g1), Re and R(b1) in Radix ginseng by HPLC. To facilitate the identification and analysis of the uncertainty sources arising from the procedure of analysis, a cause and effect diagram was const...

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Bibliographic Details
Published inYao hsüeh hsüeh pao Vol. 40; no. 1; p. 49
Main Authors Hu, Ping, Luo, Guo-an, Zhao, Zhong-zhen, Chan, Kelvin K C, Jiang, Zhi-hong
Format Journal Article
LanguageChinese
Published China 01.01.2005
Subjects
Chromatography, High Pressure Liquid - methods
Ginsenosides - analysis
Panax - chemistry
Plants, Medicinal - chemistry
Quality Control
Sensitivity and Specificity
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Summary:To set out the procedure for estimation of measurement uncertainty for the determination of ginsenosides R(g1), Re and R(b1) in Radix ginseng by HPLC. To facilitate the identification and analysis of the uncertainty sources arising from the procedure of analysis, a cause and effect diagram was constructed and simplified. Each uncertainty component whether associated with individual sources or with the combined effects of several sources, was evaluated with respect to the significance of its contribution to the overall measurement uncertainty and was expressed as standard uncertainty. All the standard uncertainties were then combined according to the appropriate rules to give a combined standard uncertainty and an expanded standard uncertainty. Results The expanded standard uncertainties for the HPLC determination of ginsenoside R(g1), Re, and R(b1), are 0.12c, 0.14c and 0.13c, respectively. Measurement uncertainty is applicable to set the limit of the ginsenosides in Radix ginseng. The establishment of the me
ISSN:0513-4870