Recurrent respiratory papillomatosis in Ibadan, Nigeria

• Published in: Nigerian journal of medicine Vol. 13; no. 3; p. 235
• Main Authors: Nwaorgu, O G B, Bakari, A A, Onakoya, P A, Ayodele, K J
• Format: Journal Article
• Language: English
• Published: Nigeria 01.07.2004
• Subjects: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Laryngeal Neoplasms - diagnosis; Laryngeal Neoplasms - therapy; Male; Neoplasm Recurrence, Local - diagnosis; Nigeria; Papilloma - diagnosis; Papilloma - therapy; Retrospective Studies; Nigeria
• ISSN: 1115-2613

Recurrent respiratory papilomatosis (RRP), the most common benign neoplasm of the larynx, usually results in upper airway obstruction that is most often misdiagnosed as lower airway disease in children. The prevalence of RRP and various aspects of its clinical course are still unknown with a dearth of literature on this in Nigeria. This study aims at presenting the clinical profile of RRP as seen in the University College Hospital, Ibadan, Nigeria. A retrospective study of 43 cases of histologically confirmed RRP over a fifteen-year period in the Otorhinolaryngology Department of the University College Hospital Ibadan. There were 28 (65.1%) males and 15 (34.9%) females with mean age of 8.7 years (range 2-23 years). Thirty-two patients (74.4%) were between 110 years with the highest incidence occurring at the 6-10 year age group (39.5%). Forty-one patients (95.3%) belonged to low social classes V and IV. Thirty-one patients (72%) presented within 1 year of onset of symptoms. All the patients were hoarse with 70% of those dyspnoeic at presentation having emergency tracheostomy. The lesions involved the vocal cords and anterior commissure mostly. There were no recurrences in 23 patients (53.5%) while twenty patients (46.5%) had 2 to 5 recurrences. Sequelae of RRP in Children may be grave, thus a high index of suspicion is needed in a patient with progressive voice change exceeding six weeks and unresponsive to standard medical therapy.